Mastering Excel's Ctrl + Arrow Key Navigation:

Learn the basic movements: Hold down Ctrl and press any arrow key (↑, ↓, ←, →) to jump to the last cell containing data before a blank cell. For example, Ctrl + ↓ takes you to the last filled cell in a column, while Ctrl + → jumps to the last filled cell in a row.

Use with Shift for selection: Add Shift to the combination (Ctrl + Shift + Arrow) to select all cells between your current position and the destination. This is perfect for quickly selecting large ranges of data without dragging your mouse.

Navigate between data regions: Double-tap the arrow key while holding Ctrl to jump past empty cells to the next data region. This is especially useful when your worksheet contains multiple separate tables or data sets.

Combine with Home/End: Press Ctrl + Home to instantly jump to cell A1, or Ctrl + End to move to the last used cell in your worksheet. These shortcuts help you quickly orient yourself in large spreadsheets.

Practice empty cell detection: Learn to recognize how Excel determines "empty" versus "filled" cells. Remember that cells with formulas returning blank values or cells with just spaces are still considered filled, affecting how the shortcuts behave.